Country-specific adaptations of global economic models aim to quantitatively determine precise estimates of economic impact and other results in the given country. The adaption process requires modification of model and inputs as required by country representatives based on HTA guidelines to make the model applicable to the country.
Our expert team developed a country-specific adaptation of an economic model to evaluate the value of an oncology therapy. The adapted model included both cost-effectiveness and a budget-impact model. Our team employed a robust, defined procedure for the country-adaptation process to ensure quality and consistency throughout the process. They began by receiving the model adaptation request from the country affiliate, followed by collection and discussion of inputs, model adaptation, and report writing. Each member of the team works independently on each task including populating the model with inputs, running the model, performing sensitivity analyses, writing the report, and model reductions as per country requirements. The team conducted multiple rounds of quality checking and validation to ensure the accuracy of the results. The country-specific adaptations of economic models ultimately help our clients to demonstrate the value and impact of launching a product in a given country.